[light music in the background throughout]
Voiceover: Hello, are you turning the dose knob of the Zepbound KwikPen, but it stops before getting to 1?
On-screen text: Lilly [LOGO]
ZEPBOUNDTM KWIKPEN (TIRZEPATIDE INJECTION)
TROUBLESHOOTING ZEPBOUND KWIKPEN: You cannot inject the next dose. The dose knob turns but stops before getting to 1 T.
REFERENCES
1-Zepbound KwikPen Instructions for Use. Eli Lilly Canada Inc.
2-Data on file, Eli Lilly and Company and or one of its subsidiaries.
Visual: Video title and text appear on the screen
Voiceover: First, let's take a look at some essential information. Each Zepbound KwikPen contains four doses, with each dose delivering a fixed volume of 0.6 mL of solution. The KwikPen includes enough medication to allow for priming before every injection. The lines on the Zepbound KwikPen are not intended to indicate the number of doses remaining in the KwikPen. This image shows the approximate plunger position after the fourth dose has been delivered.
On-screen text: ESSENTIAL INFORMATION
The Zepbound KwikPen provides 4 doses, each delivering a fixed 0.6 mL of solution, with enough included for priming before each injection. The lines on the Zepbound KwikPen are not intended to indicate the number of doses remaining in the KwikPen. The image shows approximate plunger position after delivery of the fourth dose.
Visual: Text and images appear on screen. There is an image of the Zepbound KwikPen showing the approximate plunger position after the fourth dose. Lines on the KwikPen are visible. A visual cue points to the plunger position, indicating it corresponds to the approximate plunger position after delivery of the fourth dose.
Voiceover: You should mark each dose on a calendar to help keep track of your weekly injections across 4 weeks (28 days).
On-screen text: ESSENTIAL INFORMATION
Patients should mark each dose on a calendar to help keep track of their weekly injections.
Dose 1
Dose 2
Dose 3
Dose 4
New Zepbound KwikPen Required
Visual: Text and images appear on screen. A white calendar is displayed, showing a full month view. Specific dates are circled and labeled to indicate weekly injection milestones:
Day 1: Dose 1
Day 8: Dose 2
Day 15: Dose 3
Day 22: Dose 4
Day 29: New Zepbound KwikPen Required
The layout visually reinforces the importance of tracking each weekly dose and knowing when to start using a new KwikPen.
Voiceover: To determine why this issue is occurring, you need to ask yourself if you have delivered the 4 complete doses of the Zepbound KwikPen. Take a look at the plunger position and the amount of solution left in the KwikPen, this will help you determine if you have delivered 4 doses. Expect to see medicine remaining in the KwikPen after the 4th dose has been delivered.
On-screen text: Have the 4 complete doses from the ZepboundTM KwikPen been delivered? The image below illustrates the approximate plunger position, and the medication volume left in the Zepbound KwikPen after the 4th and final dose has been delivered.
Visual: Text appears on screen. Image of plunger position and remaining solution in the KwikPen after 4th dose appears on screen. Indicator pointing to remaining solution showing that it is leftover medicine (not a dose).
Voiceover: Be mindful about the number of times you prime your KwikPen because this will lead you to lose your 4th dose.The KwikPen contains enough solution to deliver 4 complete doses with an additional amount to allow you to prime the KwikPen.
On-screen text: Has the ZepboundTM KwikPen been overprimed before injecting any of the previous 3 doses? The KwikPen contains enough solution to deliver 4 complete doses with an additional amount to allow the user to prime the KwikPen before each dose.It is important to NOT overprime the KwikPen because this will lead you to lose your 4th dose.
Visual: Text appears on screen. Image of KwikPen on the bottom of the screen
Voiceover: To prime the Zepbound KwikPen, slowly turn the dose knob until you hear 2 clicks and the extended line is shown in the dose window. This is the prime position. It can be corrected by turning the dose knob in either direction until the prime position is achieved.
On-screen text: Has the ZepboundTM KwikPen been appropriately primed? Prime position: Slowly turn the dose knob until 2 clicks are heard and the extended line is shown in the dose window. It can be corrected by turning the dose knob in either direction until the prime position is achieved.
Visual: Text appears on screen. Image of KwikPen dose knob and dosing window on the bottom of the screen. Forefinger and thumb turn the dose knob until the indicator in the dosing window is on the long hash line. Image of an arrow pointing to an ear flash in the middle of the screen showing to listen for 2 audible clicks.
Voiceover: The KwikPen has been successfully primed if a small amount of medicine comes out of the tip of the pen needle.
On-screen text: Has the ZepboundTM KwikPen been appropriately primed? The Zepbound KwikPen has been successfully primed if a small amount of medicine comes out of the tip of the pen needle. It is not necessary to see a stream of medicine to confirm a successful prime.
Visual: Text appears on screen. KwikPen held upright with needle pointing up appears on the right of the screen. Thumb pushing dose knob to release some medicine into the air until the knob stops. Then slowly counting to 5 while holding the dose knob. Close-up image of needle tip with drop of solution at the tip in the middle of the screen.
Voiceover: If you are still having trouble with these steps, check the instructions for use, or give us a call at the number on the screen.
On-screen text: Need more help? If you are still having trouble with these steps, check the instructions for use, or give us a call at 1-888-545-5972.
Visual: Image of papers and exclamation point appear in the middle of the screen.
Voiceover: Thanks for watching!
On-screen text: Lilly [LOGO]
A MEDICINE COMPANY
VV-Canada Medical-US-DEL-0352©2025 Eli Lilly Canada Inc. All rights reserved
Visual: Lilly logo appears.