[light music in the background throughout]
Voiceover: Hello, wondering why there’s medication left in the Zepbound KwikPen after the 4th dose? Let’s find out.
On-screen text: Lilly [LOGO]
ZEPBOUNDTM KwikPen® (tirzepatide injection)
Troubleshooting Zepbound KwikPen: There is medication remaining after the 4th dose.
REFERENCES
1-Zepbound KwikPen Instructions for Use. Eli Lilly Canada Inc.
2-Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Visual: Video title and text appear on the screen.
Voiceover: First, let’s take a look at some essential information. Each Zepbound KwikPen contains four doses, with each dose delivering a fixed volume of 0.6 mL of solution. The KwikPen includes enough medication to allow for priming before every injection. The lines on the Zepbound KwikPen are not intended to indicate the number of doses remaining in the KwikPen. This image shows the approximate plunger position after the fourth dose has been delivered.
On-screen text: ESSENTIAL INFORMATION
The Zepbound KwikPen provides 4 doses, each delivering a fixed 0.6 mL of solution, with enough included for priming before each injection. The lines on the Zepbound KwikPen are not intended to indicate the number of doses remaining in the KwikPen. The image shows approximate plunger position after delivery of the fourth dose.
Visual: Text and images appear on screen. There is an image of the Zepbound KwikPen showing the approximate plunger position after the fourth dose. Lines on the KwikPen are visible. A visual cue points to the plunger position, indicating it corresponds to the approximate plunger position after delivery of the fourth dose.
Voiceover: You should mark each dose on a calendar to help keep track of your weekly injections across 4 weeks (28 days).
On-screen text: Patients should mark each dose on a calendar to help keep track of their weekly injections.
Dose 1
Dose 2
Dose 3
Dose 4
New Zepbound KwikPen Required
Visual: Text and images appear on screen. A white calendar is displayed, showing a full month view. Specific dates are circled and labeled to indicate weekly injection milestones:
Day 1: Dose 1
Day 8: Dose 2
Day 15: Dose 3
Day 22: Dose 4
Day 29: New Zepbound KwikPen Required
The layout visually reinforces the importance of tracking each weekly dose and knowing when to start using a new KwikPen.
Voiceover: After administering 4 full doses over the course of a month, you may notice some medicine remaining in your Zepbound KwikPen. Rest assured; this is expected. You can confirm that all doses have been delivered by looking at the plunger position. You will see medicine remaining in the Zepbound KwikPen after the 4th dose has been delivered. An additional 0.6 mL (complete) dose cannot be dialed. Throw away the Zepbound KwikPen after taking 4 weekly doses, even though there is still medication left in it. The leftover is not sufficient for another full dose.
On-screen text: There is medicine remaining in the ZepboundTM KwikPen® after the 4th dose After 4 doses covering a month’s treatment, you may confirm that all the doses have been delivered by looking at the plunger position. Expect to see leftover medicine (not a dose) remaining in the KwikPen after the 4th dose has been delivered. An additional 0.6 ml (complete) dose cannot be dialed Throw away Zepbound the KwikPen, after receiving the 4 weekly doses.
Visual: Text appears on screen. Image of plunger position and remaining solution in the KwikPen after 4th dose. Indicator pointing to remaining solution showing that it is leftover medicine (not a dose). Image of a garbage can appears on screen with a line connecting it to the remaining solution in the KwikPen, indicating that this solution is to be thrown out after the 4th and final dose.
Voiceover: You may store your used KwikPen at room temperature, up to 30°C, for up to 30 days.
On-screen text: There is medicine remaining in the ZepboundTM KwikPen® after the 4th dose Reminder: You may store your used KwikPen at room temperature up to 30°C for up to 30 days. Lilly cannot guarantee the efficacy and safety of the medicine past 30 days after the first use.
Visual: Image of plunger position and remaining solution in the KwikPen after 4th dose. Indicator pointing to remaining solution showing that it is leftover medicine (not a dose). Image of a garbage can appears on screen with a line connecting it to the remaining solution in the KwikPen, indicating that this solution is to be thrown out after the 4th and final dose.
Voiceover: Lilly cannot guarantee the efficacy and safety of the medicine past 30 days after the first use.
On-screen text: There is medicine remaining in the ZepboundTM KwikPen® after the 4th dose Reminder: You may store your used KwikPen at room temperature up to 30°C for up to 30 days. Lilly cannot guarantee the efficacy and safety of the medicine past 30 days after the first use.
Visual: Image of plunger position and remaining solution in the KwikPen after 4th dose. Indicator pointing to remaining solution showing that it is leftover medicine (not a dose). Image of a garbage can appears on screen with a line connecting it to the remaining solution in the KwikPen, indicating that this solution is to be thrown out after the 4th and final dose.
Voiceover: Thanks for watching!
On-screen text: Lilly A MEDICINE COMPANY [LOGO]
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0351 ©2025 Eli Lilly Canada Inc.
All rights reserved.
Visual: Lilly logo appears.