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Zepbound® (tirzepatide)

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Zepbound is an injectable once-weekly prescription medicine that may help adults with obesity to lose weight and keep it off along with a reduced-calorie diet and increased physical activity. Talk to your doctor to see if Zepbound is right for you.
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LillyDirect logo
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Get Started
link
#getstarted
jump to LillyDirect Pharmacy details
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KwikPen® for Single-Patient Use

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Self-pay prices range from $299* to $449*† per month

Terms and conditions apply. Pen needle purchase required.

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Is KwikPen right for me?
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Select insurance accepted | Self-pay accepted | Free delivery | Pickup available
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Zepbound KwikPen 2.5mg/0.6mL and Zepbound logo

Zepbound KwikPen

Self-pay price:
Starting at $299/month*

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2.5 mg/0.6 mL (starting dose)
Terms and conditions apply.
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Zepbound KwikPen 5mg/0.6mL and Zepbound logo

Zepbound KwikPen

Self-pay price:
Starting at $399/month*

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5 mg/0.6 mL
Terms and conditions apply.
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Zepbound KwikPen 7.5mg/0.6mL and Zepbound logo

Zepbound KwikPen

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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7.5 mg/0.6 mL
Terms and conditions apply.
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Zepbound KwikPen 10 mg/0.6mL and Zepbound logo

Zepbound KwikPen

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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10 mg/0.6 mL
Terms and conditions apply.
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Zepbound KwikPen 12.5mg/0.6mL and Zepbound logo

Zepbound KwikPen

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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12.5 mg/0.6 mL
Terms and conditions apply.
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Zepbound KwikPen 15mg/0.6mL and Zepbound logo

Zepbound KwikPen

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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15 mg/0.6 mL
Terms and conditions apply.
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*Self-pay only. Eligibility required, terms and conditions apply. Savings subject to monthly and annual limits. Month is defined as 28-days and 1 single-patient-use KwikPen. Card eligibility and terms and conditions may be terminated, rescinded, revoked, or amended by Lilly at any time without notice and for any reason. PROGRAM IS NOT INSURANCE. Review full terms and conditions. PROGRAM IS NOT INSURANCE. Review full terms and conditions.
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For 7.5 mg, 10 mg, 12.5 mg and 15 mg doses, prices reflect monthly cost with Zepbound Journey Program. Regular prices will apply if prescription is not refilled within 45 days ($499 for 7.5mg, $699 for 10mg, $699 for 12.5mg, and $699 for 15mg). See terms and conditions. 2.5 mg is a starting dose and is not approved as a maintenance dose.
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Explore other product options for Zepbound: 
Single-Dose Vial | Single-Dose Pen
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Savings are automatically applied through LillyDirect. If you choose to fill through another pharmacy, you may need a Lilly savings program depending on your insurance type. Explore savings to get matched with a savings program. Terms and conditions apply.
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LillyDirect Pharmacy
link
#getstarted
jump to LillyDirect Pharmacy details
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Explore self-pay savings
link
https://enrollment.zepboundselfpay.lilly.com/enroll/welcome
navigate to the Zepbound enrollment services gateway
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Single-Dose Vial

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Self-pay prices range from
$299* to $449*† per month

Terms and conditions apply. Needle and syringe purchase required.

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Exclusively available through LillyDirect | Self-pay only | Free delivery | Pickup available
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Zepbound Vial 2.5mg/0.5mL and Zepbound logo

Zepbound Vial

Self-pay price:
Starting at $299/month*

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2.5 mg/0.5 mL (starting dosage)
Terms and conditions apply.
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Zepbound Vial 5mg/0.5mL and Zepbound logo

Zepbound Vial

Self-pay price:
Starting at $399/month*

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5 mg/0.5 mL
Terms and conditions apply.
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Zepbound Vial 7.5mg/0.5mL and Zepbound logo

Zepbound Vial

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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7.5 mg/0.5 mL
Terms and conditions apply.
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Zepbound Vial 10mg/0.5mL and Zepbound logo

Zepbound Vial

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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10 mg/0.5 mL
Terms and conditions apply.
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Zepbound Vial 12.5mg/0.5mL and Zepbound logo

Zepbound Vial

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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12.5 mg/0.5 mL
Terms and conditions apply.
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Zepbound Vial 15mg/0.5mL and Zepbound logo

Zepbound Vial

Self-pay price:
Starting at $449/month*

when you refill within 45 days

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15 mg/0.5 mL
Terms and conditions apply.
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*Self-pay only. Eligibility required, terms and conditions apply. Savings subject to monthly and annual limits. Month is defined as 28-days and 1 single-patient-use KwikPen. Card eligibility and terms and conditions may be terminated, rescinded, revoked, or amended by Lilly at any time without notice and for any reason. PROGRAM IS NOT INSURANCE. Review full terms and conditions.
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For 7.5 mg, 10 mg, 12.5 mg and 15 mg doses, prices reflect monthly cost with Zepbound Journey Program. Regular prices will apply if prescription is not refilled within 45 days ($499 for 7.5mg, $699 for 10mg, $699 for 12.5mg, and $699 for 15mg). See terms and conditions. 2.5 mg is a starting dose and is not approved as a maintenance dose.
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Explore other product options for Zepbound: 
KwikPen® for Single-Patient Use | Single-Dose Pen
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Savings are automatically applied through LillyDirect. Terms and conditions apply.
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LillyDirect Pharmacy
link
#getstarted
jump to LillyDirect Pharmacy details
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Explore self-pay savings
link
https://zepboundselfpay.enrollment.lilly.com
On click, navigate to the Zepbound enrollment services gateway
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Single-Dose Pen

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Pay as low as $25* for up to a 3-month prescription, if eligible and commercially insured with coverage for Zepbound

Terms and conditions apply. Needle included in each Pen.

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Insurance accepted | Free delivery
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Zepbound Pen 2.5mg/0.5mL and Zepbound logo

Zepbound Single-Dose Pen

Insurance price:
Pay as low as $25* for up to a 3-month prescription

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2.5 mg/0.5 mL (starting dosage)
Terms and conditions apply.
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Zepbound Pen 5mg/0.5mL and Zepbound logo

Zepbound Single-Dose Pen

Insurance price:
Pay as low as $25* for up to a 3-month prescription

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5 mg/0.5 mL
Terms and conditions apply.
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Zepbound Pen 7.5mg/0.5mL and Zepbound logo

Zepbound Single-Dose Pen

Insurance price:
Pay as low as $25* for up to a 3-month prescription

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7.5 mg/0.5 mL
Terms and conditions apply.
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Zepbound Pen 10mg/0.5mL and Zepbound logo

Zepbound Single-Dose Pen

Insurance price:
Pay as low as $25* for up to a 3-month prescription

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10 mg/0.5 mL
Terms and conditions apply.
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Zepbound Pen 12.5mg/0.5mL and Zepbound logo

Zepbound Single-Dose Pen

Insurance price:
Pay as low as $25* for up to a 3-month prescription

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12.5 mg/0.5 mL
Terms and conditions apply.
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Zepbound Pen 15mg/0.5mL and Zepbound logo

Zepbound Single-Dose Pen

Insurance price:
Pay as low as $25* for up to a 3-month prescription

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15 mg/0.5 mL
Terms and conditions apply.
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*Governmental beneficiaries excluded. Eligibility required, terms and conditions apply. Savings subject to monthly and annual limits. Month is defined as 28-days and up to 4 single-dose pens. Card eligibility and terms and conditions may be terminated, rescinded, revoked, or amended by Lilly at any time without notice and for any reason. PROGRAM IS NOT INSURANCE. Review full terms and conditions.
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Governmental beneficiaries include any state, federal, or government funded healthcare program, like Medicaid, Medicare, Medicare Part D, Medicare Advantage, Medigap, DoD, VA, TRICARE®/CHAMPUS, or any state prescription drug assistance program.
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Explore other product options for Zepbound: Single-Dose Vial | 
KwikPen® for Single-Patient Use
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The Zepbound® single‑dose pen could be the most cost‑effective option for you if you have commercial insurance that covers it and if you meet the eligibility requirements for the savings card. Access Lilly's coverage checker tool to get matched with a savings program. Terms and conditions apply.
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Verify your coverage
link
https://lillycoveragecheck.iassist.com/zep
navigate to zepbound's coverage checker
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Explore self-pay savings
link
https://zepboundselfpay.enrollment.lilly.com
On click, navigate to the Zepbound enrollment services gateway
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How to get started with Zepbound

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Zepbound is available through LillyDirect and retail pharmacies for patients who are insured or plan to self-pay without using insurance. No matter your insurance status, there’s an option for you. Start by talking to your doctor to see if Zepbound is right for you, then follow the steps below.
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Prescription icon

Step 1

Ask your doctor to send your prescription to:

LillyDirect Pharmacy
NPI: 1912889320 | NCPDP: 1574056
1555 S Harding St, Ste 171-B68, 
Indianapolis, IN 46221

If you need help finding a doctor, we can connect you with virtual and in-person care.
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Prescription icon

Step 2

Once your prescription is received, a pharmacy partner will reach out to guide you through the next steps. They’ll help confirm details, explore any available savings, choose pharmacy options, and let you know when your medicine is ready for checkout.
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What to expect next
pdf
https://delivery-p137454-e1438138.adobeaemcloud.com/adobe/assets/urn:aaid:aem:9e49612a-3619-4733-936f-351c70861ba0/renditions/original/as/LillyDirect-Nonbranded-Consumer-Expectations-Guide.pdf?assetname=LillyDirect+Nonbranded+Consumer+Expectations+Guide.pdf
On click, open the consumer expectations guide
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Are you a healthcare provider looking for prescribing information for Zepbound?

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Learn how to prescribe
asset
https://lilly.com/lillydirect/hcp?medicine=foundayo_tablet
https://delivery-p137454-e1438138.adobeaemcloud.com/adobe/assets/urn:aaid:aem:544069d2-cf3d-4043-91a6-f63784285485/renditions/original/as/zepbound_Vial_Guide.pdf?assetname=zepbound_Vial_Guide.pdf
navigate to the Zepbound prescribing guide for LillyDirect
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Prescribing Guide
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Zepbound INJECTION TYPES

Which option is right for me?

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Zepbound comes in three different formats. Learn about your injection options.
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KwikPen® for Single-Patient Use

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KwikPen is a multi-dose pen that holds four doses of Zepbound medicine, one for each week of the month. Each injection uses a new pen needle, and you can purchase pen needles at checkout. KwikPen is available through LillyDirect self-pay with free home delivery or retail pickup at Walmart Pharmacy.

Explore Zepbound KwikPen for Single-Patient Use

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Single-Dose Vial

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The single-dose vial holds one dose of Zepbound medicine (each monthly prescription contains four once-weekly vials). Each injection uses a new needle and syringe, which you can purchase at checkout. Vial is available exclusively through LillyDirect self-pay. You can choose between free home delivery or free retail pickup at Walmart Pharmacy.

Explore Zepbound Single-Dose Vial

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Single-Dose Pen

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The single-dose pen holds one dose of Zepbound medicine, with a built-in needle that you never have to see or handle. Each monthly prescription contains four single-dose pens. The single‑dose pen could also be the most cost‑effective option for you if you have commercial insurance that covers it and if you meet the eligibility requirements for the savings card.

Explore Zepbound Single-Dose Pen

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TALK TO A DOCTOR

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Find an obesity specialist

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Obesity specialists can be hard to find, but they don't have to be.
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Photograph of a person sitting at a counter and looking at their phone in their hands.

Get independent virtual care

Independent virtual care for obesity management, no matter where you are.

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Enjoy the benefits of:

  • Insurance Coverage: Options available depending on your provider.
  • Personalized Plans: Tailored obesity management plans just for you.
  • Comprehensive Support: Access to resources and ongoing assistance.
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Learn more
link
/find-care/telehealth/obesity
Learn more about independent virtual care provider options for obesity
Photograph of a person looking down while their doctor is listening with a stethoscope

Find independent in-person care

Healthgrades is an independent search tool. Search for care by what matters most to you.

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Filter by:

  • Insurance
  • Specialty
  • Distance
  • And more!
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Search now
link
/find-care/in-person-care?condition=obesity
Search for independent in-person care providers
embedded-tools-healthgrades
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LillyDirect weight management medicines

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Understanding your treatment options is an important part of managing your weight and your health. Get clear information about our weight management medicines so that you can have more informed conversations with your doctor.
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Explore your options
link
https://www.lilly.com/lillydirect/medicines/weight-management
navigate to explore the offerings available through LillyDirect
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Real medicine, real support, right on time

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Free delivery or pickup

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We deliver authentic Lilly medicines to your home, if prescribed. We can also provide support if you choose pickup at a retail pharmacy near you.
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Personalized savings

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With LillyDirect, you get personalized savings support and trusted guidance that makes getting your prescription easier every step of the way.
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Coverage support

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We automatically check your insurance coverage routinely and support you if prior authorization is required.
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There's more to LillyDirect

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LillyDirect delivers medication, support with your health journey, and resources to keep you moving forward.
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LIllyDirect logo
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Explore LillyDirect
link
https://www.lilly.com/lillydirect
explore all medicines available through LillyDirect Pharmacy
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Frequently asked questions

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How can I get Zepbound?

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Zepbound requires a valid prescription from a licensed healthcare provider. Ask your doctor to send your prescription to LillyDirect Pharmacy:

LillyDirect Pharmacy
NPI: 1912889320 | NCPDP: 1574056
1555 S Harding St, Ste 171-B68, Indianapolis, IN 46221

If you need help finding a doctor, we can connect you with virtual and in-person care. You can choose a local doctor using Healthgrades, an independent physician search tool, or connect with an independent virtual care team for convenient, specialized support.

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Do I need to purchase needles for the KwikPen and Vial?

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Yes, you will need to purchase injection supplies for both the KwikPen and Vial. You can purchase supplies through LillyDirect checkout, at a local pharmacy, or online.

For KwikPen, a new pen needle is required for each weekly injection. Injection supplies, including pen needles, can be added to your cart at checkout or purchased separately. KwikPen needles are different from the needles required for the Vial.

For Vial, a new needle and syringe are required for each weekly injection. Injection supplies can be added to your cart at checkout or purchased separately.

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How do I manage my Zepbound prescription?

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You can manage your Zepbound prescription through LillyDirect. If prescribed, LillyDirect will manage your order from prescription to delivery. We provide coverage support, savings guidance, assistance with prior authorization, and delivery options to make getting your prescription as easy as possible.
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I was on a different medication and want to switch to Zepbound. Which dose should I start on?

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The recommended starting dose of Zepbound is 2.5 mg. Your healthcare provider may increase your dose in 2.5 mg increments after at least 4 weeks until the recommended maintenance dose is reached.

If you are switching from another medication, it’s important to talk to your healthcare provider about the right approach for you.

Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines. It is not known if Zepbound is safe and effective for use in children.

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How do LillyDirect's pharmacy services work?

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LillyDirect is a different kind of pharmacy experience. We work with licensed third-party pharmacy service providers to give you personalized access to a convenient pharmacy experience.

Current pharmacy providers are detailed below.

Prescryptive® is a third-party healthcare technology company connecting the healthcare ecosystem to put consumers first. Through Prescryptive®, you have digital control over your prescriptions, helping you understand your medication costs and find ways to pay less.

Amazon Pharmacy is a full-service, digital first pharmacy offering wide selection, medication details, 24/7 U.S.-licensed pharmacist support, and a familiar Amazon shopping journey that includes upfront pricing. Amazon Pharmacy delivers quickly and securely to all 50 U.S. states with FREE shipping, allowing most customers to receive their medications in 1-4 days. Same-day delivery is available in select metropolitan areas. Most insurance plans are accepted, including Medicare and Medicaid, and multiple savings options are available, including automatic coupons.

Fuze Health is a healthcare solutions company that provides a wide range of pharmacy dispensing services including online ordering, insurance and manufacturer savings processing, order notifications, refill reminders, and prescription renewals. It owns and operates several mail-order pharmacies that accept most insurance plans and ship medications nationwide. A team of licensed pharmacists ensures medications are safely and securely dispensed and shipped, and knowledgeable support professionals are available 24/7 to answer your questions.

Gifthealth is a third-party, self-pay pharmacy fulfillment provider. When you purchase Lilly medication through Gifthealth, you will have the option to receive discreet home delivery or pick up your medication at retail location near you. By selecting this option to purchase Lilly medication, you agree not to seek payment or accept reimbursement, either directly or indirectly, from any insurance plan or other third-party payer.

Walmart Pharmacy is a full-service pharmacy offering patients the convenience of in-store prescription pickup at over 4,600 locations nationwide. Walmart offers patients the convenience of picking up their eligible LillyDirect medications from their local pharmacy.  By selecting this option to purchase Lilly medication, you agree not to seek payment or accept reimbursement, either directly or indirectly, from any insurance plan or other third-party payer.

Information will be updated when additional service providers are added.

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What if I have a medical-related question?
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For medical-related questions, contact The Lilly Answers Center at 1-800-545-5979.
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CUSTOMER SUPPORT

We’re here to help

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For help with refills, the Zepbound Self-Pay Journey Program, or questions about your medicine, call LillyDirect at:

1-844-559-3471

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For medical-related questions, contact The Lilly Answers Center at

1-800-545-5979

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Your feedback = 
better experiences

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Take the survey
link
https://www.lilly.com/lillydirect/feedback-survey
On click, navigate to LillyDirect survey
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LillyDirect®, Zepbound®, its delivery device base, and KwikPen® are registered trademarks of Eli Lilly and Company.

CMAT-05333 05/2026 ©Lilly USA, LLC 2026. All rights reserved.

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